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The Neutral Sphingomyelinase Pathway Regulates Packaging of the Prion Protein into Exosomes

Prion diseases are a group of transmissible, fatal neurodegenerative disorders associated with the misfolding of the host-encoded prion protein, PrP(C), into a disease-associated form, PrP(Sc). The transmissible prion agent is principally formed of PrP(Sc) itself and is associated with extracellular...

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Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Guo, Belinda B., Bellingham, Shayne A., Hill, Andrew F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319014/
https://ncbi.nlm.nih.gov/pubmed/25505180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.605253
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