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Role of Cyclophilin A from Brains of Prion-infected Mice in Stimulation of Cytokine Release by Microglia and Astroglia in Vitro

Prion diseases or transmissible spongiform encephalopathy diseases are typically characterized by deposition of abnormally folded partially protease-resistant host-derived prion protein (PrPres), which is associated with activated glia and increased release of cytokines. This neuroinflammatory respo...

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Autori principali: Tribouillard-Tanvier, Déborah, Carroll, James A., Moore, Roger A., Striebel, James F., Chesebro, Bruce
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281647/
https://ncbi.nlm.nih.gov/pubmed/22179611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.269480
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