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Mechanistic Insights into Hsp104 Potentiation

Potentiated variants of Hsp104, a protein disaggregase from yeast, can dissolve protein aggregates connected to neurodegenerative diseases such as Parkinson disease and amyotrophic lateral sclerosis. However, the mechanisms underlying Hsp104 potentiation remain incompletely defined. Here, we establi...

詳細記述

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書誌詳細
出版年:J Biol Chem
主要な著者: Torrente, Mariana P., Chuang, Edward, Noll, Megan M., Jackrel, Meredith E., Go, Michelle S., Shorter, James
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777845/
https://ncbi.nlm.nih.gov/pubmed/26747608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.707976
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