Mechanistic Insights into Hsp104 Potentiation

Potentiated variants of Hsp104, a protein disaggregase from yeast, can dissolve protein aggregates connected to neurodegenerative diseases such as Parkinson disease and amyotrophic lateral sclerosis. However, the mechanisms underlying Hsp104 potentiation remain incompletely defined. Here, we establi...

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Spremljeno u:
Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Torrente, Mariana P., Chuang, Edward, Noll, Megan M., Jackrel, Meredith E., Go, Michelle S., Shorter, James
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Protein Structure and Folding
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777845/
https://ncbi.nlm.nih.gov/pubmed/26747608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.707976
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