Mutations in Complement Factor H Impair Alternative Pathway Regulation on Mouse Glomerular Endothelial Cells in Vitro

Complement factor H (FH) inhibits complement activation and interacts with glomerular endothelium via its complement control protein domains 19 and 20, which also recognize heparan sulfate (HS). Abnormalities in FH are associated with the renal diseases atypical hemolytic uremic syndrome and dense d...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Loeven, Markus A., Rops, Angelique L., Lehtinen, Markus J., van Kuppevelt, Toin H., Daha, Mohamed R., Smith, Richard J., Bakker, Marinka, Berden, Jo H., Rabelink, Ton J., Jokiranta, T. Sakari, van der Vlag, Johan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2016
Gaiak:
Glycobiology and Extracellular Matrices
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777835/
https://ncbi.nlm.nih.gov/pubmed/26728463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.702506
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