Differential binding of chemokines CXCL1, CXCL2 and CCL2 to mouse glomerular endothelial cells reveals specificity for distinct heparan sulfate domains

INTRODUCTION: Proliferative glomerulonephritis manifests in a range of renal diseases and is characterized by the influx of inflammatory cells into the glomerulus. Heparan sulfate (HS) is an important (co-)receptor for binding of chemokines, cytokines and leukocytes to the endothelial glycocalyx, a...

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Pubblicato in:PLoS One
Autori principali: van Gemst, J. J., Kouwenberg, M., Rops, A. L. W. M. M., van Kuppevelt, T. H., Berden, J. H., Rabelink, T. J., Loeven, M. A., van der Vlag, J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152867/
https://ncbi.nlm.nih.gov/pubmed/30248108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201560
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