The Heparan Sulfate Motif (GlcNS6S-IdoA2S)(3), Common in Heparin, Has a Strict Topography and Is Involved in Cell Behavior and Disease

Heparan sulfate (HS) is a structurally complex polysaccharide that interacts with a broad spectrum of extracellular effector ligands and thereby is thought to regulate a diverse array of biologic processes. The specificity of HS-ligand interactions is determined by the arrangement of sulfate groups...

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Main Authors: Smits, Nicole C., Kurup, Sindhulakshmi, Rops, Angelique L., ten Dam, Gerdy B., Massuger, Leon F., Hafmans, Theo, Turnbull, Jeremy E., Spillmann, Dorothe, Li, Jin-ping, Kennel, Stephen J., Wall, Jonathan S., Shworak, Nicholas W., Dekhuijzen, P. N. Richard, van der Vlag, Johan, van Kuppevelt, Toin H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Glycobiology and Extracellular Matrices
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003412/
https://ncbi.nlm.nih.gov/pubmed/20837479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.153791
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