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Pathogenic Ubqln2 gains toxic properties to induce neuron death
Mutations in ubiquilin 2 (Ubqln2) is linked to amyotrophic lateral sclerosis and frontotemporal lobar degeneration. A foremost question regarding Ubqln2 pathogenesis is whether pathogenically mutated Ubqln2 causes neuron death via a gain or loss of functions. To better understand Ubqln2 pathobiology...
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| Publicat a: | Acta Neuropathol |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4777328/ https://ncbi.nlm.nih.gov/pubmed/25388785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-014-1367-y |
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