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Regulation of global gene expression and cell proliferation by APP

Down syndrome (DS), caused by trisomy of chromosome 21, is one of the most common genetic disorders. Patients with DS display growth retardation and inevitably develop characteristic Alzheimer’s disease (AD) neuropathology, including neurofibrillary tangles and neuritic plaques. The expression of am...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Wu, Yili, Zhang, Si, Xu, Qin, Zou, Haiyan, Zhou, Weihui, Cai, Fang, Li, Tingyu, Song, Weihong
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776145/
https://ncbi.nlm.nih.gov/pubmed/26936520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22460
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