Regulation of global gene expression and cell proliferation by APP

Down syndrome (DS), caused by trisomy of chromosome 21, is one of the most common genetic disorders. Patients with DS display growth retardation and inevitably develop characteristic Alzheimer’s disease (AD) neuropathology, including neurofibrillary tangles and neuritic plaques. The expression of am...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Wu, Yili, Zhang, Si, Xu, Qin, Zou, Haiyan, Zhou, Weihui, Cai, Fang, Li, Tingyu, Song, Weihong
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776145/
https://ncbi.nlm.nih.gov/pubmed/26936520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22460
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