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Regulation of global gene expression and cell proliferation by APP

Down syndrome (DS), caused by trisomy of chromosome 21, is one of the most common genetic disorders. Patients with DS display growth retardation and inevitably develop characteristic Alzheimer’s disease (AD) neuropathology, including neurofibrillary tangles and neuritic plaques. The expression of am...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wu, Yili, Zhang, Si, Xu, Qin, Zou, Haiyan, Zhou, Weihui, Cai, Fang, Li, Tingyu, Song, Weihong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776145/
https://ncbi.nlm.nih.gov/pubmed/26936520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22460
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