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GS-5806 Inhibits a Broad Range of Respiratory Syncytial Virus Clinical Isolates by Blocking the Virus-Cell Fusion Process

Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infections in infants and young children. In addition, RSV causes significant morbidity and mortality in hospitalized elderly and immunocompromised patients. Currently, only palivizumab, a monoclonal antibody against the...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Perron, Michel, Stray, Kirsten, Kinkade, April, Theodore, Dorothy, Lee, Gary, Eisenberg, Eugene, Sangi, Michael, Gilbert, Brian E., Jordan, Robert, Piedra, Pedro A., Toms, Geoffery L., Mackman, Richard, Cihlar, Tomas
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776015/
https://ncbi.nlm.nih.gov/pubmed/26666922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01497-15
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