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Efficacy and Safety of AFN-1252, the First Staphylococcus-Specific Antibacterial Agent, in the Treatment of Acute Bacterial Skin and Skin Structure Infections, Including Those in Patients with Significant Comorbidities

This open-label noncontrolled, phase II multicenter trial was designed to evaluate the safety, tolerability, and efficacy of 200 mg of AFN-1252, a selective inhibitor of Staphylococcus aureus enoyl-acyl carrier protein reductase (FabI), given by mouth twice daily in the treatment of acute bacterial...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Antimicrob Agents Chemother
Main Authors: Hafkin, B., Kaplan, N., Murphy, B.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775962/
https://ncbi.nlm.nih.gov/pubmed/26711777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01741-15
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