Perturbation of Staphylococcus aureus Gene Expression by the Enoyl-Acyl Carrier Protein Reductase Inhibitor AFN-1252

This study examines the alteration in Staphylococcus aureus gene expression following treatment with the type 2 fatty acid synthesis inhibitor AFN-1252. An Affymetrix array study showed that AFN-1252 rapidly increased the expression of fatty acid synthetic genes and repressed the expression of virul...

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Detalhes bibliográficos
Main Authors: Parsons, Joshua B., Kukula, Maciej, Jackson, Pamela, Pulse, Mark, Simecka, Jerry W., Valtierra, David, Weiss, William J., Kaplan, Nachum, Rock, Charles O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632907/
https://ncbi.nlm.nih.gov/pubmed/23459481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02307-12
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