טוען...

Differential Mechanisms of Tenofovir and Tenofovir Disoproxil Fumarate Cellular Transport and Implications for Topical Preexposure Prophylaxis

Intravaginal rings releasing tenofovir (TFV) or its prodrug, tenofovir disoproxil fumarate (TDF), are being evaluated for HIV and herpes simplex virus (HSV) prevention. The current studies were designed to determine the mechanisms of drug accumulation in human vaginal and immune cells. The exposure...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Antimicrob Agents Chemother
Main Authors: Taneva, Ekaterina, Crooker, Kerry, Park, Sung Hyun, Su, Jonathan T., Ott, Adina, Cheshenko, Natalia, Szleifer, Igal, Kiser, Patrick F., Frank, Bruce, Mesquita, Pedro M. M., Herold, Betsy C.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775922/
https://ncbi.nlm.nih.gov/pubmed/26711762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02793-15
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