Vaginally Delivered Tenofovir Disoproxil Fumarate Provides Greater Protection than Tenofovir against Genital Herpes in a Murine Model of Efficacy and Safety

Increased susceptibility to genital herpes in medroxyprogesterone-treated mice may provide a surrogate of increased HIV risk and a preclinical biomarker of topical preexposure prophylaxis safety. We evaluated tenofovir disoproxil fumarate (TDF) in this murine model because an intravaginal ring eluti...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Nixon, Briana, Jandl, Thomas, Teller, Ryan S., Taneva, Ekaterina, Wang, Yanhua, Nagaraja, Umadevi, Kiser, Patrick F., Herold, Betsy C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910864/
https://ncbi.nlm.nih.gov/pubmed/24323471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01818-13
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky