Vaginally Delivered Tenofovir Disoproxil Fumarate Provides Greater Protection than Tenofovir against Genital Herpes in a Murine Model of Efficacy and Safety

Increased susceptibility to genital herpes in medroxyprogesterone-treated mice may provide a surrogate of increased HIV risk and a preclinical biomarker of topical preexposure prophylaxis safety. We evaluated tenofovir disoproxil fumarate (TDF) in this murine model because an intravaginal ring eluti...

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Xehetasun bibliografikoak
Egile Nagusiak: Nixon, Briana, Jandl, Thomas, Teller, Ryan S., Taneva, Ekaterina, Wang, Yanhua, Nagaraja, Umadevi, Kiser, Patrick F., Herold, Betsy C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2014
Gaiak:
Antiviral Agents
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910864/
https://ncbi.nlm.nih.gov/pubmed/24323471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01818-13
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