Vaginally Delivered Tenofovir Disoproxil Fumarate Provides Greater Protection than Tenofovir against Genital Herpes in a Murine Model of Efficacy and Safety

Increased susceptibility to genital herpes in medroxyprogesterone-treated mice may provide a surrogate of increased HIV risk and a preclinical biomarker of topical preexposure prophylaxis safety. We evaluated tenofovir disoproxil fumarate (TDF) in this murine model because an intravaginal ring eluti...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Nixon, Briana, Jandl, Thomas, Teller, Ryan S., Taneva, Ekaterina, Wang, Yanhua, Nagaraja, Umadevi, Kiser, Patrick F., Herold, Betsy C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910864/
https://ncbi.nlm.nih.gov/pubmed/24323471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01818-13
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker