Safety, Immunogenicity, and Protective Efficacy of Intradermal Immunization with Aseptic, Purified, Cryopreserved Plasmodium falciparum Sporozoites in Volunteers under Chloroquine Prophylaxis: A Randomized Controlled Trial

Immunization of volunteers under chloroquine prophylaxis by bites of Plasmodium falciparum sporozoite (PfSPZ)–infected mosquitoes induces > 90% protection against controlled human malaria infection (CHMI). We studied intradermal immunization with cryopreserved, infectious PfSPZ in volunteers taki...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Am J Trop Med Hyg
Main Authors: Bastiaens, Guido J. H., van Meer, Maurits P. A., Scholzen, Anja, Obiero, Joshua M., Vatanshenassan, Mansoureh, van Grinsven, Tim, Kim Lee Sim, B., Billingsley, Peter F., James, Eric R., Gunasekera, Anusha, Bijker, Else M., van Gemert, Geert-Jan, van de Vegte-Bolmer, Marga, Graumans, Wouter, Hermsen, Cornelus C., de Mast, Quirijn, van der Ven, André J. A. M., Hoffman, Stephen L., Sauerwein, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Tropical Medicine and Hygiene 2016
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4775905/
https://ncbi.nlm.nih.gov/pubmed/26711509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.15-0621
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados