Controlled Human Malaria Infections by Intradermal Injection of Cryopreserved Plasmodium falciparum Sporozoites

Controlled human malaria infection with sporozoites is a standardized and powerful tool for evaluation of malaria vaccine and drug efficacy but so far only applied by exposure to bites of Plasmodium falciparum (Pf)-infected mosquitoes. We assessed in an open label Phase 1 trial, infection after intr...

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Auteurs principaux: Roestenberg, Meta, Bijker, Else M., Sim, B. Kim Lee, Billingsley, Peter F., James, Eric R., Bastiaens, Guido J. H., Teirlinck, Anne C., Scholzen, Anja, Teelen, Karina, Arens, Theo, van der Ven, André J. A. M., Gunasekera, Anusha, Chakravarty, Sumana, Velmurugan, Soundarapandian, Hermsen, Cornelus C., Sauerwein, Robert W., Hoffman, Stephen L.
Format: Artigo
Langue:Inglês
Publié: The American Society of Tropical Medicine and Hygiene 2013
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541746/
https://ncbi.nlm.nih.gov/pubmed/23149582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.2012.12-0613
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