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Protection against malaria after immunization by chloroquine prophylaxis and sporozoites is mediated by preerythrocytic immunity
Volunteers immunized under chloroquine chemoprophylaxis with Plasmodium falciparum sporozoites (CPS) develop complete, long-lasting protection against homologous sporozoite challenge. Chloroquine affects neither sporozoites nor liver-stages, but kills only asexual forms in erythrocytes once released...
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| Principais autores: | , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3651438/ https://ncbi.nlm.nih.gov/pubmed/23599283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220360110 |
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