c-MYB is a transcriptional regulator of ESPL1/Separase in BCR-ABL-positive chronic myeloid leukemia

BACKGROUND: Genomic instability and clonal evolution are hallmarks of progressing chronic myeloid leukemia (CML). Recently, we have shown that clonal evolution and blast crisis correlate with altered expression and activity of Separase, a cysteine endopeptidase that is a mitotic key player in chromo...

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Bibliografische gegevens
Gepubliceerd in:Biomark Res
Hoofdauteurs: Prinzhorn, Wiltrud, Stehle, Michael, Kleiner, Helga, Ruppenthal, Sabrina, Müller, Martin C., Hofmann, Wolf-Karsten, Fabarius, Alice, Seifarth, Wolfgang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4774018/
https://ncbi.nlm.nih.gov/pubmed/26937281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40364-016-0059-2
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