Clonal Evolution and Blast Crisis Correlate with Enhanced Proteolytic Activity of Separase in BCR-ABL b3a2 Fusion Type CML under Imatinib Therapy

Unbalanced (major route) additional cytogenetic aberrations (ACA) at diagnosis of chronic myeloid leukemia (CML) indicate an increased risk of progression and shorter survival. Moreover, newly arising ACA under imatinib treatment and clonal evolution are considered features of acceleration and defin...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Haaß, Wiltrud, Kleiner, Helga, Weiß, Christel, Haferlach, Claudia, Schlegelberger, Brigitte, Müller, Martin C., Hehlmann, Rüdiger, Hofmann, Wolf-Karsten, Fabarius, Alice, Seifarth, Wolfgang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4472749/
https://ncbi.nlm.nih.gov/pubmed/26087013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129648
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller