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Two active site divalent ions in the crystal structure of the hammerhead ribozyme bound to a transition state analog
The crystal structure of the hammerhead ribozyme bound to the pentavalent transition state analog vanadate reveals significant rearrangements relative to the previously solved structures. The active site contracts, bringing G10.1 closer to the cleavage site, and repositioning a divalent metal ion su...
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| Publicado no: | Biochemistry |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4773901/ https://ncbi.nlm.nih.gov/pubmed/26551631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b01139 |
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