Observations on catalysis by hammerhead ribozymes are consistent with a two-divalent-metal-ion mechanism
Significant cleavage by hammerhead ribozymes requires activation by divalent metal ions. Several models have been proposed to account for the influence of metal ions on hammerhead activity. A number of recent papers have presented data that have been interpreted as supporting a one-metal-hydroxide-i...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1997
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20080/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9122187/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.6.2290 |
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