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Metal ion cooperativity in ribozyme cleavage of RNA

Combinations of chemical and genetic approaches were used to study the function of divalent metal ions in cleavage of RNA by the ribozyme RNase P RNA. We show that different divalent metal ions have differential effects on cleavage site recognition and rescue of cleavage activity by mixing divalent...

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Detalles Bibliográficos
Main Authors: Brännvall, Mathias, Kirsebom, Leif A.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC60804/
https://ncbi.nlm.nih.gov/pubmed/11606743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.221456598
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