Intralymphatic mRNA vaccine induces CD8 T-cell responses that inhibit the growth of mucosally located tumours

The lack of appropriate mouse models is likely one of the reasons of a limited translational success rate of therapeutic vaccines against cervical cancer, as rapidly growing ectopic tumours are commonly used for preclinical studies. In this work, we demonstrate that the tumour microenvironment of TC...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bialkowski, Lukasz, van Weijnen, Alexia, Van der Jeught, Kevin, Renmans, Dries, Daszkiewicz, Lidia, Heirman, Carlo, Stangé, Geert, Breckpot, Karine, Aerts, Joeri L., Thielemans, Kris
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773884/
https://ncbi.nlm.nih.gov/pubmed/26931556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22509
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