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mRNA: From a chemical blueprint for protein production to an off-the-shelf therapeutic

Two decades ago, mRNA became the focus of research in molecular medicine and was proposed as an active pharmaceutical ingredient for the therapy of cancer. In this regard, mRNA has been mainly used for ex vivo modification of antigen-presenting cells (APCs), such as dendritic cells (DCs). This vacci...

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書目詳細資料
Main Authors: Van Lint, Sandra, Heirman, Carlo, Thielemans, Kris, Breckpot, Karine
格式: Artigo
語言:Inglês
出版: Landes Bioscience 2013
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859745/
https://ncbi.nlm.nih.gov/pubmed/23291946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.22661
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