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mRNA: From a chemical blueprint for protein production to an off-the-shelf therapeutic

Two decades ago, mRNA became the focus of research in molecular medicine and was proposed as an active pharmaceutical ingredient for the therapy of cancer. In this regard, mRNA has been mainly used for ex vivo modification of antigen-presenting cells (APCs), such as dendritic cells (DCs). This vacci...

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Detalhes bibliográficos
Main Authors: Van Lint, Sandra, Heirman, Carlo, Thielemans, Kris, Breckpot, Karine
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859745/
https://ncbi.nlm.nih.gov/pubmed/23291946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.22661
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