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Intratumoral delivery of mRNA: Overcoming obstacles for effective immunotherapy

The immunosuppressive tumor microenvironment (TME) is a major obstacle in cancer immunotherapy. Therefore, it has gained attention as a target site. mRNA emerged as a versatile drug class for cancer therapy. We reported that intratumoral administration of mRNA encoding the fusokine Fβ(2) supports tu...

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Vydáno v:Oncoimmunology
Hlavní autoři: Van der Jeught, Kevin, Van Lint, Sandra, Thielemans, Kris, Breckpot, Karine
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4485825/
https://ncbi.nlm.nih.gov/pubmed/26155403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1005504
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