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Overcoming HLA restriction in clinical trials: Immune monitoring of mRNA-loaded DC therapy

A decade of collective work by tumor immunologists has led to improved large scale generation, maturation, antigen loading and administration of dendritic cells (DCs) to cancer patients, promoting enhanced antitumor activity. We alleviated the HLA-restriction in DC therapy and demonstrated that it i...

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Bibliografiske detaljer
Main Authors: Van Nuffel, An M.T., Wilgenhof, Sofie, Thielemans, Kris, Bonehill, Aude
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518513/
https://ncbi.nlm.nih.gov/pubmed/23243604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.20926
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