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Overcoming HLA restriction in clinical trials: Immune monitoring of mRNA-loaded DC therapy

A decade of collective work by tumor immunologists has led to improved large scale generation, maturation, antigen loading and administration of dendritic cells (DCs) to cancer patients, promoting enhanced antitumor activity. We alleviated the HLA-restriction in DC therapy and demonstrated that it i...

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Detalhes bibliográficos
Main Authors: Van Nuffel, An M.T., Wilgenhof, Sofie, Thielemans, Kris, Bonehill, Aude
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518513/
https://ncbi.nlm.nih.gov/pubmed/23243604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.20926
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