Characterization of CD8(+) T-Cell Responses in the Peripheral Blood and Skin Injection Sites of Melanoma Patients Treated with mRNA Electroporated Autologous Dendritic Cells (TriMixDC-MEL)

Treatment of melanoma patients with mRNA electroporated dendritic cells (TriMixDC-MEL) stimulates T-cell responses against the presented tumor-associated antigens (TAAs). In the current clinical trials, melanoma patients with systemic metastases are treated, requiring priming and/or expansion of pre...

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Autores principales: Benteyn, Daphné, Van Nuffel, An M. T., Wilgenhof, Sofie, Corthals, Jurgen, Heirman, Carlo, Neyns, Bart, Thielemans, Kris, Bonehill, Aude
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581259/
https://ncbi.nlm.nih.gov/pubmed/23509826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/976383
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