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Overcoming HLA restriction in clinical trials: Immune monitoring of mRNA-loaded DC therapy

A decade of collective work by tumor immunologists has led to improved large scale generation, maturation, antigen loading and administration of dendritic cells (DCs) to cancer patients, promoting enhanced antitumor activity. We alleviated the HLA-restriction in DC therapy and demonstrated that it i...

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Главные авторы: Van Nuffel, An M.T., Wilgenhof, Sofie, Thielemans, Kris, Bonehill, Aude
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518513/
https://ncbi.nlm.nih.gov/pubmed/23243604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.20926
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