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mRNA: From a chemical blueprint for protein production to an off-the-shelf therapeutic

Two decades ago, mRNA became the focus of research in molecular medicine and was proposed as an active pharmaceutical ingredient for the therapy of cancer. In this regard, mRNA has been mainly used for ex vivo modification of antigen-presenting cells (APCs), such as dendritic cells (DCs). This vacci...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Van Lint, Sandra, Heirman, Carlo, Thielemans, Kris, Breckpot, Karine
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Landes Bioscience 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859745/
https://ncbi.nlm.nih.gov/pubmed/23291946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/hv.22661
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