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Caveolin interaction governs Kv1.3 lipid raft targeting

The spatial localization of ion channels at the cell surface is crucial for their functional role. Many channels localize in lipid raft microdomains, which are enriched in cholesterol and sphingolipids. Caveolae, specific lipid rafts which concentrate caveolins, harbor signaling molecules and their...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Pérez-Verdaguer, Mireia, Capera, Jesusa, Martínez-Mármol, Ramón, Camps, Marta, Comes, Núria, Tamkun, Michael M., Felipe, Antonio
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773814/
https://ncbi.nlm.nih.gov/pubmed/26931497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22453
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