Unconventional EGF-induced ERK1/2-mediated Kv1.3 endocytosis

The potassium channel Kv1.3 plays roles in immunity, neuronal development and sensory discrimination. Regulation of Kv1.3 by kinase signaling has been studied. In this context, EGF binds to specific receptors (EGFR) and triggers tyrosine kinase-dependent signaling, which down-regulates Kv1.3 current...

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Bibliografische gegevens
Gepubliceerd in:Cell Mol Life Sci
Hoofdauteurs: Martínez-Mármol, Ramón, Comes, Núria, Styrczewska, Katarzyna, Pérez-Verdaguer, Mireia, Vicente, Rubén, Pujadas, Lluís, Soriano, Eduardo, Sorkin, Alexander, Felipe, Antonio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer International Publishing 2015
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836834/
https://ncbi.nlm.nih.gov/pubmed/26542799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-015-2082-0
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