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Unconventional EGF-induced ERK1/2-mediated Kv1.3 endocytosis
The potassium channel Kv1.3 plays roles in immunity, neuronal development and sensory discrimination. Regulation of Kv1.3 by kinase signaling has been studied. In this context, EGF binds to specific receptors (EGFR) and triggers tyrosine kinase-dependent signaling, which down-regulates Kv1.3 current...
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| Publicado no: | Cell Mol Life Sci |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4836834/ https://ncbi.nlm.nih.gov/pubmed/26542799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-015-2082-0 |
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