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Ubiquitination mediates Kv1.3 endocytosis as a mechanism for protein kinase C-dependent modulation
The voltage-dependent potassium channel Kv1.3 plays essential physiological functions in the immune system. Kv1.3, regulating the membrane potential, facilitates downstream Ca(2+) -dependent pathways and becomes concentrated in specific membrane microdomains that serve as signaling platforms. Increa...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5301257/ https://ncbi.nlm.nih.gov/pubmed/28186199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42395 |
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