Unconventional EGF-induced ERK1/2-mediated Kv1.3 endocytosis

The potassium channel Kv1.3 plays roles in immunity, neuronal development and sensory discrimination. Regulation of Kv1.3 by kinase signaling has been studied. In this context, EGF binds to specific receptors (EGFR) and triggers tyrosine kinase-dependent signaling, which down-regulates Kv1.3 current...

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Bibliografiska uppgifter
I publikationen:Cell Mol Life Sci
Huvudupphovsmän: Martínez-Mármol, Ramón, Comes, Núria, Styrczewska, Katarzyna, Pérez-Verdaguer, Mireia, Vicente, Rubén, Pujadas, Lluís, Soriano, Eduardo, Sorkin, Alexander, Felipe, Antonio
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer International Publishing 2015
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836834/
https://ncbi.nlm.nih.gov/pubmed/26542799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-015-2082-0
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