A novel mitochondrial Kv1.3–caveolin axis controls cell survival and apoptosis

The voltage-gated potassium channel Kv1.3 plays an apparent dual physiological role by participating in activation and proliferation of leukocytes as well as promoting apoptosis in several types of tumor cells. Therefore, Kv1.3 is considered a potential pharmacological target for immunodeficiency an...

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Bibliographic Details
Published in:eLife
Main Authors: Capera, Jesusa, Pérez-Verdaguer, Mireia, Peruzzo, Roberta, Navarro-Pérez, María, Martínez-Pinna, Juan, Alberola-Die, Armando, Morales, Andrés, Leanza, Luigi, Szabó, Ildiko, Felipe, Antonio
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2021
Subjects:
Cancer Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8248986/
https://ncbi.nlm.nih.gov/pubmed/34196606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.69099
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