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Caveolin interaction governs Kv1.3 lipid raft targeting

The spatial localization of ion channels at the cell surface is crucial for their functional role. Many channels localize in lipid raft microdomains, which are enriched in cholesterol and sphingolipids. Caveolae, specific lipid rafts which concentrate caveolins, harbor signaling molecules and their...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Pérez-Verdaguer, Mireia, Capera, Jesusa, Martínez-Mármol, Ramón, Camps, Marta, Comes, Núria, Tamkun, Michael M., Felipe, Antonio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773814/
https://ncbi.nlm.nih.gov/pubmed/26931497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22453
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