Intraoral Mitochondrial-Targeted GS-Nitroxide, JP4-039, Radioprotects Normal Tissue in Tumor-Bearing Radiosensitive Fancd2(−/−) (C57BL/6) Mice

We evaluated normal tissue specific radioprotection of the oral cavity in radiosensitive Fanconi Anemia (FA) Fancd2(−/−)mice with orally established tumors using mitochondrial-targeted GS-nitroxide (JP4-039). Adult (10–12 weeks old) Fancd2(+/+), Fancd2(+/−) and Fancd2(−/−) mice (C57BL/6 background)...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Radiat Res
Prif Awduron: Shinde, Ashwin, Berhane, Hebist, Rhieu, Byung Han, Kalash, Ronny, Xu, Karen, Goff, Julie, Epperly, Michael W., Franicola, Darcy, Zhang, Xichen, Dixon, Tracy, Shields, Donna, Wang, Hong, Wipf, Peter, Parmar, Kalindi, Guinan, Eva, Kagan, Valerian, Tyurin, Vladimir, Ferris, Robert L., Zhang, Xiaolan, Li, Song, Greenberger, Joel S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773657/
https://ncbi.nlm.nih.gov/pubmed/26789701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR14035.1
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg