Intraoral Mitochondrial-Targeted GS-Nitroxide, JP4-039, Radioprotects Normal Tissue in Tumor-Bearing Radiosensitive Fancd2(−/−) (C57BL/6) Mice

We evaluated normal tissue specific radioprotection of the oral cavity in radiosensitive Fanconi Anemia (FA) Fancd2(−/−)mice with orally established tumors using mitochondrial-targeted GS-nitroxide (JP4-039). Adult (10–12 weeks old) Fancd2(+/+), Fancd2(+/−) and Fancd2(−/−) mice (C57BL/6 background)...

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Bibliografiset tiedot
Julkaisussa:Radiat Res
Päätekijät: Shinde, Ashwin, Berhane, Hebist, Rhieu, Byung Han, Kalash, Ronny, Xu, Karen, Goff, Julie, Epperly, Michael W., Franicola, Darcy, Zhang, Xichen, Dixon, Tracy, Shields, Donna, Wang, Hong, Wipf, Peter, Parmar, Kalindi, Guinan, Eva, Kagan, Valerian, Tyurin, Vladimir, Ferris, Robert L., Zhang, Xiaolan, Li, Song, Greenberger, Joel S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4773657/
https://ncbi.nlm.nih.gov/pubmed/26789701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR14035.1
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