Amelioration of Head and Neck Radiation-Induced Mucositis and Distant Marrow Suppression in Fanca(−/−) and Fancg(−/−) Mice by Intraoral Administration of GS-Nitroxide (JP4-039)

Squamous cell carcinomas of the head and neck are appearing with increased frequency in both marrow transplanted and non-transplanted Fanconi anemia (FA) patients. FA patients commonly display radiosensitivity of epithelial tissues, complicating effective radiotherapy. Fancd2(−/−) mice (C57BL/6J and...

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Detalhes bibliográficos
Publicado no:Radiat Res
Main Authors: Willis, John, Epperly, Michael W., Fisher, Renee, Zhang, Xichen, Shields, Donna, Hou, Wen, Wang, Hong, Li, Song, Wipf, Peter, Parmar, Kalindi, Guinan, Eva, Steinman, Justin, Greenberger, Joel S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5973476/
https://ncbi.nlm.nih.gov/pubmed/29584588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR14878.1
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