Extensive respiratory chain defects in inhibitory interneurones in patients with mitochondrial disease

AIMS: Mitochondrial disorders are among the most frequently inherited cause of neurological disease and arise due to mutations in mitochondrial or nuclear DNA. Currently, we do not understand the specific involvement of certain brain regions or selective neuronal vulnerability in mitochondrial disea...

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Veröffentlicht in:Neuropathol Appl Neurobiol
Hauptverfasser: Lax, Nichola Z., Grady, John, Laude, Alex, Chan, Felix, Hepplewhite, Philippa D., Gorman, Grainne, Whittaker, Roger G., Ng, Yi, Cunningham, Mark O., Turnbull, Doug M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2015
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772453/
https://ncbi.nlm.nih.gov/pubmed/25786813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nan.12238
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