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Mitochondrial DNA Depletion in Respiratory Chain–Deficient Parkinson Disease Neurons
OBJECTIVE: To determine the extent of respiratory chain abnormalities and investigate the contribution of mtDNA to the loss of respiratory chain complexes (CI–IV) in the substantia nigra (SN) of idiopathic Parkinson disease (IPD) patients at the single‐neuron level. METHODS: Multiple‐label immunoflu...
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| Publicado no: | Ann Neurol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4819690/ https://ncbi.nlm.nih.gov/pubmed/26605748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24571 |
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