Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons

Mitochondrial dysfunction is implicated in the pathophysiology of Parkinson′s disease (PD), a common age-associated neurodegenerative disease characterized by intraneuronal inclusions (Lewy bodies) and progressive degeneration of the nigrostriatal dopamine (DA) system. It has recently been demonstra...

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Detalhes bibliográficos
Main Authors: Ekstrand, Mats I., Terzioglu, Mügen, Galter, Dagmar, Zhu, Shunwei, Hofstetter, Christoph, Lindqvist, Eva, Thams, Sebastian, Bergstrand, Anita, Hansson, Fredrik Sterky, Trifunovic, Aleksandra, Hoffer, Barry, Cullheim, Staffan, Mohammed, Abdul H., Olson, Lars, Larsson, Nils-Göran
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783140/
https://ncbi.nlm.nih.gov/pubmed/17227870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605208103
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