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Investigating complex I deficiency in Purkinje cells and synapses in patients with mitochondrial disease

AIMS: Cerebellar ataxia is common in patients with mitochondrial disease, and despite previous neuropathological investigations demonstrating vulnerability of the olivocerebellar pathway in patients with mitochondrial disease, the exact neurodegenerative mechanisms are still not clear. We use quanti...

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Detalhes bibliográficos
Publicado no:Neuropathol Appl Neurobiol
Main Authors: Chrysostomou, Alexia, Grady, John P., Laude, Alex, Taylor, Robert W., Turnbull, Doug M., Lax, Nichola Z.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973693/
https://ncbi.nlm.nih.gov/pubmed/26337858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nan.12282
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