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Investigating complex I deficiency in Purkinje cells and synapses in patients with mitochondrial disease

AIMS: Cerebellar ataxia is common in patients with mitochondrial disease, and despite previous neuropathological investigations demonstrating vulnerability of the olivocerebellar pathway in patients with mitochondrial disease, the exact neurodegenerative mechanisms are still not clear. We use quanti...

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Dades bibliogràfiques
Publicat a:Neuropathol Appl Neurobiol
Autors principals: Chrysostomou, Alexia, Grady, John P., Laude, Alex, Taylor, Robert W., Turnbull, Doug M., Lax, Nichola Z.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973693/
https://ncbi.nlm.nih.gov/pubmed/26337858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nan.12282
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