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The genetics and pathology of mitochondrial disease

Mitochondria are double‐membrane‐bound organelles that are present in all nucleated eukaryotic cells and are responsible for the production of cellular energy in the form of ATP. Mitochondrial function is under dual genetic control – the 16.6‐kb mitochondrial genome, with only 37 genes, and the nucl...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Alston, Charlotte L, Rocha, Mariana C, Lax, Nichola Z, Turnbull, Doug M, Taylor, Robert W
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215404/
https://ncbi.nlm.nih.gov/pubmed/27659608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4809
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