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Development of passive CLARITY and immunofluorescent labelling of multiple proteins in human cerebellum: understanding mechanisms of neurodegeneration in mitochondrial disease

CLARITY enables immunofluorescent labelling and imaging of large volumes of tissue to provide a better insight into the three dimensional relationship between cellular morphology and spatial interactions between different cell types. In the current study, we optimise passive CLARITY and immunofluore...

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Publicat a:Sci Rep
Autors principals: Phillips, Jonathan, Laude, Alex, Lightowlers, Robert, Morris, Chris M., Turnbull, Doug M., Lax, Nichola Z.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867607/
https://ncbi.nlm.nih.gov/pubmed/27181107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26013
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