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Development of passive CLARITY and immunofluorescent labelling of multiple proteins in human cerebellum: understanding mechanisms of neurodegeneration in mitochondrial disease

CLARITY enables immunofluorescent labelling and imaging of large volumes of tissue to provide a better insight into the three dimensional relationship between cellular morphology and spatial interactions between different cell types. In the current study, we optimise passive CLARITY and immunofluore...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Phillips, Jonathan, Laude, Alex, Lightowlers, Robert, Morris, Chris M., Turnbull, Doug M., Lax, Nichola Z.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867607/
https://ncbi.nlm.nih.gov/pubmed/27181107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26013
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