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The Cell-Cycle Arrest and Apoptotic Functions of p53 in Tumor Initiation and Progression
P53 is a transcription factor highly inducible by many stress signals such as DNA damage, oncogene activation, and nutrient deprivation. Cell-cycle arrest and apoptosis are the most prominent outcomes of p53 activation. Many studies showed that p53 cell-cycle and apoptosis functions are important fo...
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| Publicado no: | Cold Spring Harb Perspect Med |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4772082/ https://ncbi.nlm.nih.gov/pubmed/26931810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026104 |
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