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The Cell-Cycle Arrest and Apoptotic Functions of p53 in Tumor Initiation and Progression

P53 is a transcription factor highly inducible by many stress signals such as DNA damage, oncogene activation, and nutrient deprivation. Cell-cycle arrest and apoptosis are the most prominent outcomes of p53 activation. Many studies showed that p53 cell-cycle and apoptosis functions are important fo...

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Bibliografski detalji
Izdano u:Cold Spring Harb Perspect Med
Glavni autor: Chen, Jiandong
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772082/
https://ncbi.nlm.nih.gov/pubmed/26931810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026104
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